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1

NONCODING RNAS IN THE MAMMALIAN CENTRAL NERVOUS SYSTEM

Cao, Xinwei, Yeo, Gene, Muotri, Alysson R., Kuwabara, Tomoko, Gage, Fred H.

Journal:

Annual Review of Neuroscience

Year:

2006

Language:

english

File:

PDF, 519 KB

english, 2006

2

Implication of silence in a Japanese psychotherapy context: a preliminary study using quantitative analysis of silence and utterance of a therapist and a client

Nagaoka, Chika, Kuwabara, Tomoko, Yoshikawa, Sakiko, Watabe, Motoki, Komori, Masashi, Oyama, Yasuhiro, Hatanaka, Chihiro

Journal:

Asia Pacific Journal of Counselling and Psychotherapy

Year:

2013

Language:

english

File:

PDF, 325 KB

english, 2013

3

Clinical and magnetic resonance imaging features of elderly onset dentatorubral–pallidoluysian atrophy

Sugiyama, Atsuhiko, Sato, Noriko, Nakata, Yasuhiro, Kimura, Yukio, Enokizono, Mikako, Maekawa, Tomoko, Kondo, Madoka, Takahashi, Yuji, Kuwabara, Satoshi, Matsuda, Hiroshi

Journal:

Journal of Neurology

Year:

2017

Language:

english

File:

PDF, 1.31 MB

english, 2017

4

Association of Genetic Risks With Autism Spectrum Disorder and Early Neurodevelopmental Delays Among Children Without Intellectual Disability

Takahashi, Nagahide, Harada, Taeko, Nishimura, Tomoko, Okumura, Akemi, Choi, Damee, Iwabuchi, Toshiki, Kuwabara, Hitoshi, Takagai, Shu, Nomura, Yoko, Takei, Nori, Tsuchiya, Kenji J.

Journal:

JAMA Network Open

Year:

2020

Language:

english

File:

PDF, 635 KB

english, 2020

5

A Synthetic Small Molecule That Induces Neuronal Differentiation of Adult Hippocampal Neural Progenitor Cells

Masaki Warashina, Kyung Hoon Min, Tomoko Kuwabara, Alexis Huynh, Fred H. Gage, Peter G. Schultz, Sheng Ding

Journal:

Angewandte Chemie

Year:

2006

Language:

english

File:

PDF, 359 KB

english, 2006

6

A Synthetic Small Molecule That Induces Neuronal Differentiation of Adult Hippocampal Neural Progenitor Cells

Masaki Warashina, Kyung Hoon Min, Tomoko Kuwabara, Alexis Huynh, Fred H. Gage, Peter G. Schultz, Sheng Ding

Journal:

Angewandte Chemie International Edition

Year:

2006

Language:

english

File:

PDF, 359 KB

english, 2006

7

Insulin biosynthesis in neuronal progenitors derived from adult hippocampus and the olfactory bulb

Tomoko Kuwabara, Mohamedi N. Kagalwala, Yasuko Onuma, Yuzuru Ito, Masaki Warashina, Kazuyuki Terashima, Tsukasa Sanosaka, Kinichi Nakashima, Fred H. Gage, Makoto Asashima

Journal:

EMBO Molecular Medicine

Year:

2011

Language:

english

File:

PDF, 1.22 MB

english, 2011

8

Structure–activity relationship study on the 6-membered heteroaromatic ring system of diphenylpyrazine-type prostacyclin receptor agonists

Tetsuo Asaki, Taisuke Hamamoto, Yukiteru Sugiyama, Keiichi Kuwano, Kenji Kuwabara, Tomoko Niwa

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 675 KB

english, 2007

9

Effects of cetyltrimethylammonium bromide on reactions catalyzed by maxizymes, a novel class of metalloenzymes

Aya Nakayama, Masaki Warashina, Tomoko Kuwabara, Kazunari Taira

Journal:

Journal of Inorganic Biochemistry

Year:

2000

Language:

english

File:

PDF, 1.13 MB

english, 2000

10

Development of a highly sensitive high-performance liquid chromatographic method for measuring an anticancer drug, UCN-01, in human plasma or urine

Noriaki Kurata, Tomoko Kuramitsu, Hiromi Tanii, Eiichi Fuse, Takashi Kuwabara, Hiroyuki Kobayashi, Satoshi Kobayashi

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1998

Language:

english

File:

PDF, 92 KB

english, 1998

11

Extremely high and specific activity of DNA enzymes in cells with a Philadelphia chromosome

Masaki Warashina, Tomoko Kuwabara, Yuka Nakamatsu, Kazunari Taira

Journal:

Chemistry & Biology

Year:

1999

Language:

english

File:

PDF, 2.27 MB

english, 1999

12

Allosterically controllable ribozymes with biosensor functions

Tomoko Kuwabara, Masaki Warashina, Kazunari Taira

Journal:

Current Opinion in Chemical Biology

Year:

2000

Language:

english

File:

PDF, 323 KB

english, 2000

13

Significant activity of a modified ribozyme with N7-deazaguanine at G10.1: the double-metal-ion mechanism of catalysis in reactions catalysed by hammerhead ribozymes

Yuka Nakamatsu, Masaki Warashina, Tomoko Kuwabara, Yoshiyuki Tanaka, Koichi Yoshinari, Kazunari Taira

Journal:

Year:

2000

Language:

english

File:

PDF, 457 KB

english, 2000

14

Efficient inhibition of β-secretase gene expression in HEK293 cells by tRNAVal-driven and CTE-helicase associated hammerhead ribozymes

Barbara Nawrot, Slawomir Antoszczyk, Maria Maszewska, Tomoko Kuwabara, Masaki Warashina, Kazunari Taira, Wojciech J. Stec

Journal:

Year:

2003

Language:

english

File:

PDF, 218 KB

english, 2003

15

Pharmacokinetics, distribution, metabolism and excretion of [3H]UCN-01 in rats and dogs after intravenous administration

Kenichi Yasoshima, Takashi Kuwabara, Eiichi Fuse, Tomoko Kuramitu, Noriaki Kurata, Hiroyoshi Nishiie, Takayoshi Oishi, Hiroyuki Kobayashi, Satoshi Kobayashi

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2001

Language:

english

File:

PDF, 117 KB

english, 2001

16

Transport of intracellularly active ribozymes to the cytoplasm

Makoto Miyagishi, Tomoko Kuwabara, Kazunari Taira

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2001

Language:

english

File:

PDF, 188 KB

english, 2001

17

Effect of vitamin D supplementation in the institutionalized elderly

Masako Himeno, Naoko Tsugawa, Akiko Kuwabara, Minori Fujii, Nobuko Kawai, Yuzuru Kato, Noriko Kihara, Tomoko Toyoda, Masami Kishimoto, Yoko Ogawa, Shoko Kido, Toshiaki Noike, Toshio Okano, Kiyoshi Tan

Journal:

Journal of Bone and Mineral Metabolism

Year:

2009

Language:

english

File:

PDF, 237 KB

english, 2009

18

Chemical and enzymatic probing of effector-mediated changes in the conformation of a maxizyme

Jing-Min Zhou, Yuka Nakamatsu, Tomoko Kuwabara, Masaki Warashina, Yoshiyuki Tanaka, Koichi Yoshinari, Kazunari Taira

Journal:

Journal of Inorganic Biochemistry

Year:

2000

Language:

english

File:

PDF, 908 KB

english, 2000

19

Determination of the anticancer drug KW-2170, a pyrazoloacridone derivative, and its metabolites in human and dog plasma by high-performance liquid chromatography using an electrochemical detector

Tomoko Kuramitsu, Katsumi Takai, Rui Ohashi, Takashi Kuwabara

Journal:

Journal of Chromatography B

Year:

2002

Language:

english

File:

PDF, 107 KB

english, 2002

20

10.1038/35020190

Taira, Kazunari, Tanabe, Tsuyoshi, Kuwabara, Tomoko, Warashina, Masaki, Tani, Kenzaburo, Asano, Shigetaka

Journal:

Year:

2000

Language:

english

File:

PDF, 150 KB

english, 2000

21

Formation of a catalytically active dimer by tRNAVal -driven short ribozymes

Kuwabara, Tomoko, Warashina, Masaki, Orita, Masaya, Koseki, Shiori, Ohkawa, Jun, Taira, Kazunari

Journal:

Year:

1998

File:

PDF, 838 KB

1998

22

Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis

Kuwabara, Tomoko, Hsieh, Jenny, Muotri, Alysson, Yeo, Gene, Warashina, Masaki, Lie, Dieter Chichung, Moore, Lynne, Nakashima, Kinichi, Asashima, Makoto, Gage, Fred H

Journal:

Nature Neuroscience

Year:

2009

Language:

english

File:

PDF, 1.22 MB

english, 2009

23

Allosterically controllable maxizymes cleave mRNA with high efficiency and specificity

Tomoko Kuwabara, Masaki Warashina, Kazunari Taira

Journal:

Trends in Biotechnology

Year:

2000

Language:

english

File:

PDF, 235 KB

english, 2000

24

Working at the Cutting Edge: the Creation of Allosteric Ribozymes

Masaki Warashina, Tomoko Kuwabara, Kazunari Taira

Journal:

Year:

2000

Language:

english

File:

PDF, 549 KB

english, 2000

25

Pathogenesis of lupus-like nephritis through autoimmune antibody produced by CD180-negative B lymphocytes in NZBWF1 mouse

Kazuko Fujita, Yoshikiyo Akasaka, Taku Kuwabara, Bing Wang, Kaoru Tanaka, Itaru Kamata, Tomoko Yokoo, Toshio Kinoshita, Ami Iuchi, Yuri Akishima-Fukasawa, Yukio Ishikawa, Motonari Kondo, Toshiharu Ish

Journal:

Immunology Letters

Year:

2012

Language:

english

File:

PDF, 931 KB

english, 2012

26

Extrinsic cues and intracellular epigenetic regulations that control adult neurogenesis

Tomoko Kuwabara, Kazuyuki Terashima, Masaki Warashina, Makoto Asashima

Journal:

Neuroscience Research

Year:

2011

Language:

english

File:

PDF, 86 KB

english, 2011

27

Evaluation of immunological status in tumor-bearing dogs

Hiroshi Itoh, Yutaka Horiuchi, Teppei Nagasaki, Iwao Sakonju, Tomoko Kakuta, Ushio Fukushima, Tsuyoshi Uchide, Mariko Yamashita, Masato Kuwabara, Sei-ichi Yusa, Katsuaki Takase

Journal:

Veterinary Immunology and Immunopathology

Year:

2009

Language:

english

File:

PDF, 243 KB

english, 2009

28

Significant change in the structure of a ribozyme upon introduction of a phosphorothioate linkage at P9: NMR reveals a conformational fluctuation in the core region of a hammerhead ribozyme

Ken-ichi Suzumura, Masaki Warashina, Koichi Yoshinari, Yoshiyuki Tanaka, Tomoko Kuwabara, Masaya Orita, Kazunari Taira

Journal:

Year:

2000

Language:

english

File:

PDF, 197 KB

english, 2000

29

Activation of phospholipase C-Ca2+ system by sphingosine 1-phosphate in CHO cells transfected with Edg-3, a putative lipid receptor

Koichi Sato, Junko Kon, Hideaki Tomura, Mizuho Osada, Naoya Murata, Atsushi Kuwabara, Tomoko Watanabe, Hideo Ohta, Michio Ui, Fumikazu Okajima

Journal:

Year:

1999

Language:

english

File:

PDF, 174 KB

english, 1999

30

CTAB-mediated enrichment for active forms of novel dimeric maxizymes

Aya Nakayama, Tomoko Kuwabara, Masaki Warashina, Kazunari Taira

Journal:

Year:

1999

Language:

english

File:

PDF, 543 KB

english, 1999

31

Specificity of novel allosterically trans- and cis-activated connected maxizymes that are designed to suppress BCR-ABL expression

Makiko Hamada, Tomoko Kuwabara, Masaki Warashina, Aya Nakayama, Kazunari Taira

Journal:

Year:

1999

Language:

english

File:

PDF, 809 KB

english, 1999

32

A Small Modulatory dsRNA Specifies the Fate of Adult Neural Stem Cells

Tomoko Kuwabara, Jenny Hsieh, Kinichi Nakashima, Kazunari Taira, Fred H Gage

Journal:

Year:

2004

Language:

english

File:

PDF, 2.68 MB

english, 2004

33

A Novel Allosterically trans-Activated Ribozyme, the Maxizyme, with Exceptional Specificity In Vitro and In Vivo

Tomoko Kuwabara, Masaki Warashina, Tsuyoshi Tanabe, Kenzaburo Tani, Shigetaka Asano, Kazunari Taira

Journal:

Year:

1998

Language:

english

File:

PDF, 533 KB

english, 1998

34

Astrocytes secreting paracrine factors control hippocampal aging and neurogenesis

Terashima, Kazuyuki, Okamoto, Masashiro, Inoue, Koshiro, Iwamura, Hiroki, Soya, Hideaki, Asashima, Makoto, Kuwabara, Tomoko

Journal:

Neuroscience Research

Year:

2011

Language:

english

File:

PDF, 124 KB

english, 2011

35

tRNAVal-heterodimeric Maxizymes with High Potential as Gene-Inactivating Agents: Simultaneous Cleavage at Two Sites in HIV-1 tat mRNA in Cultured Cells

Tomoko Kuwabara, Masaki Warashina, Aya Nakayama, Jun Ohkawa and Kazunari Taira

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.76 MB

english, 1999

36

Wnt Protein-mediated Satellite Cell Conversion in Adult and Aged Mice Following Voluntary Wheel Running

Fujimaki, Shin, Hidaka, Ryo, Asashima, Makoto, Takemasa, Tohru, Kuwabara, Tomoko

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.73 MB

english, 2014

37

Entropically Driven Enhancement of Cleavage Activity of a DNA-Armed Hammerhead Ribozyme: Mechanism of Action of Hammerhead Ribozymes

Warashina, Masaki, Takagi, Yasuomi, Sawata, Shinya, Zhou, De-Min, Kuwabara, Tomoko, Taira, Kazunari

Journal:

Journal of Organic Chemistry

Year:

1997

Language:

english

File:

PDF, 204 KB

english, 1997

38

Recognition of Engineered tRNAs with an Extended 3‘ End by Exportin-t (Xpo-t) and Transport of tRNA-Attached Ribozymes to the Cytoplasm in Somatic Cells

Kuwabara, Tomoko, Warashina, Masaki, Sano, Masayuki, Tang, Hengli, Wong-Staal, Flossie, Munekata, Eisuke, Taira, Kazunari

Journal:

Biomacromolecules

Year:

2001

Language:

english

File:

PDF, 1.85 MB

english, 2001

39

Allosterically Controlled Single-Chained Maxizymes with Extremely High and Specific Activity

Kuwabara, Tomoko, Hamada, Makiko, Warashina, Masaki, Taira, Kazunari

Journal:

Biomacromolecules

Year:

2001

Language:

english

File:

PDF, 1.18 MB

english, 2001

40

Allosterically Controllable Maxizyme-Mediated Suppression of Progression of Leukemia in Mice

Kuwabara, Tomoko, Tanabe, Tsuyoshi, Warashina, Masaki, Xiong, Kang Xi, Tani, Kenzaburo, Taira, Kazunari, Asano, Shigetaka

Journal:

Biomacromolecules

Year:

2001

Language:

english

File:

PDF, 1.84 MB

english, 2001

41

Maxizymes, Novel Allosterically Controllable Ribozymes, Can Be Designed To Cleave Various Substrates

Tanabe, Tsuyoshi, Takata, Iichiro, Kuwabara, Tomoko, Warashina, Masaki, Kawasaki, Hiroaki, Tani, Kenzaburo, Ohta, Shigeo, Asano, Shigetaka, Taira, Kazunari

Journal:

Biomacromolecules

Year:

2000

Language:

english

File:

PDF, 215 KB

english, 2000

42

A Reappraisal, Based on 31 P NMR, of the Direct Coordination of a Metal Ion with the Phosphoryl Oxygen at the Cleavage Site of a Hammerhead Ribozyme

Suzumura, Ken-ichi, Yoshinari, Koichi, Tanaka, Yoshiyuki, Takagi, Yasuomi, Kasai, Yasuhiro, Warashina, Masaki, Kuwabara, Tomoko, Orita, Masaya, Taira, Kazunari

Journal:

Journal of the American Chemical Society

Year:

2002

Language:

english

File:

PDF, 113 KB

english, 2002

43

Analysis of the Conserved P9-G10.1 Metal-Binding Motif in Hammerhead Ribozymes with an Extra Nucleotide Inserted between A9 and G10.1 Residues

Warashina, Masaki, Kuwabara, Tomoko, Nakamatsu, Yuka, Takagi, Yasuomi, Kato, Yoshio, Taira, Kazunari

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 442 KB

english, 2004

44

Identification of Astrocyte-expressed Factors That Modulate Neural Stem/Progenitor Cell Differentiation

Barkho, Basam Z., Song, Hongjun, Aimone, James B., Smrt, Richard D., Kuwabara, Tomoko, Nakashima, Kinichi, Gage, Fred H., Zhao, Xinyu

Journal:

Stem Cells and Development

Year:

2006

Language:

english

File:

PDF, 7.38 MB

english, 2006

45

Novel Method for Selection of tRNA-Driven Ribozymes with Enhanced Stability in Mammalian Cells

Sano, Masayuki, Kuwabara, Tomoko, Warashina, Masaki, Fukamizu, Akiyoshi, Taira, Kazunari

Journal:

Antisense and Nucleic Acid Drug Development

Year:

2002

Language:

english

File:

PDF, 529 KB

english, 2002

46

Intrinsic Ability of Adult Stem Cell in Skeletal Muscle: An Effective and Replenishable Resource to the Establishment of Pluripotent Stem Cells

Fujimaki, Shin, Machida, Masanao, Hidaka, Ryo, Asashima, Makoto, Takemasa, Tohru, Kuwabara, Tomoko

Journal:

Stem Cells International

Year:

2013

Language:

english

File:

PDF, 1.90 MB

english, 2013

47

The Insulin Regulatory Network in Adult Hippocampus and Pancreatic Endocrine System

Machida, Masanao, Fujimaki, Shin, Hidaka, Ryo, Asashima, Makoto, Kuwabara, Tomoko

Journal:

Stem Cells International

Year:

2012

Language:

english

File:

PDF, 306 KB

english, 2012

48

Pleiotrophin triggers inflammation and increased peritoneal permeability leading to peritoneal fibrosis

Yokoi, Hideki, Kasahara, Masato, Mori, Kiyoshi, Ogawa, Yoshihisa, Kuwabara, Takashige, Imamaki, Hirotaka, Kawanishi, Tomoko, Koga, Kenichi, Ishii, Akira, Kato, Yukiko, Mori, Keita P, Toda, Naohiro, Oh

Journal:

Kidney International

Year:

2012

Language:

english

File:

PDF, 508 KB

english, 2012

49

IGF-I Instructs Multipotent Adult Neural Progenitor Cells to Become Oligodendrocytes

Jenny Hsieh, James B. Aimone, Brian K. Kaspar, Tomoko Kuwabara, Kinichi Nakashima and Fred H. Gage

Journal:

The Journal of Cell Biology

Year:

2004

Language:

english

File:

PDF, 4.34 MB

english, 2004

50

Diabetes Impairs Wnt3-Induced Neurogenesis in Olfactory Bulbs via glutamate transporter 1 inhibition

Wakabayashi, Tamami, Hidaka, Ryo, Fujimaki, Shin, Asashima, Makoto, Kuwabara, Tomoko

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 4.56 MB

english, 2016

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